His starting line-up for the Euro 2020 Group D clash against England is a matter of hot debate across the nation as Scotland look to bounce back from the disappointment of the opening 2-0 defeat to the Czech Republic at Hampden on Monday.
Clarke is likely to make changes for the huge fixture, but how many, and which players are brought in, is anyone’s guess.
The Scotsman football writers have had their say and picked their own starting XI for the Auld Enemy showdown in a 3-5-1-1 formatiom.
Do you agree with our line-up?
5. RWB - James Forrest
Looked lively when he came off the bench on Monday and could give Scotland a more attacking outlook if deployed down the right flank at Wembley Photo: Alan Harvey - SNS Group
6. LWB - Andy Robertson
The Scotland skipper was a driving force down the left against the Czechs and is now starting to answer the critics who say he doesn't bring his Liverpool form to the international stage. Will be key to the nation's hopes of causing an upset at Wembley. Photo: Craig Williamson - SNS Group
7. MRC - Callum McGregor
Dropped to the bench for the Scots' Euro 2020 opener but a recall at Wembley could be on the cards as Clarke looks for the right balance in midfield. Photo: Alan Harvey - SNS Group
8. MC - Scott McTominay
Didn't get on the ball often enough against the Czechs but the Man Utd midfielder's ability to control the game will be needed at Wembley Photo: Craig Williamson - SNS Group