The arrival of Joe Hart is likely to mean a change in the goalkeeping position but there could be other tweaks to the team as the Greek-Australian coach looks for his first win at the fourth attempt following the Champions League exit to FC Midtjylland and the opening Scottish Premiership defeat to Hearts.
New signing Kyogo Furuhashi could also make his first Celtic start after earning his debut off the bench in the loss at Tynecastle, with Postecoglou stating that the Japanese forward is looking sharp and ready to play a “bigger part” than he did at the weekend.
However, James McCarthy, who also joined the Hoops this week following his departure from Crystal Palace, will not feature as he is not considered match ready and has not travelled with the squad to the Czech Republic.
Ryan Christie could also come into the manager’s thoughts after a substitute appearance at the weekend as Postecoglou considers freshening up his attack in the search for a winning formula.
Here is our predicted Celtic starting XI for the big match against the Czech side:
9. AMC - Ryan Christie
The Scotland midfielder's high-energy pressing will be an asset against the Czechs - and could see him displace David Turnbull in the number 10 role Photo: Rob Casey - SNS Group
10. AML - Kyogo Furuhashi
Postecoglou has said his new Japanese signing is fit and ready to play a bigger part than he did against Hearts - where he was introduced with 11 minutes left. Photo: Craig Williamson - SNS Group
11. FC - Odsonne Edouard
Last season's top scorer has drawn a blank in his first three matches under Postecoglou but is expected to lead the line again Photo: Ross Parker - SNS Group